ea0017p25 | (1) | BSPED2008
Mason A
, Boyd DST
, Perry RJ
, Wong SC
, Wallace AM
, Hunter I
, Ahmed SF
, Shaikh MG
Background: PPNAD is a rare form of bilateral adrenal hyperplasia associated with Carney complex and PRKAR1A mutation. We report the experience of monitoring disease activity in two patients with PPNAD.Both patients (case 1: a 7.4-year-old boy and case 2: a 6.1-year-old girl) presented with rapid onset of cushingoid symptoms, weight gain and hypertension together with multiple freckles and lentigines.Biochemical analysis on both pa...